Ĭura FA, L’Allier PL, Kapadia SR, Houghtaling PL, Dipaola LM, Ellis SG, Topol EJ, Brener SJ (2001) Predictors and prognosis of suboptimal coronary blood flow after primary coronary angioplasty in patients with acute myocardial infarction. ĭe Luca G, Ernst N, Zijlstra F, Van’t Hof AWJ, Hoorntje JCA, Dambrink JHE, Gosslink ATM, De Boer MJ, Suryapranata H (2004) Preprocedural TIMI flow and mortality in patients with acute myocardial infarction treated by primary angioplasty. Stone GW, Cox D, Garcia E, Brodie BR, Morice M-C, Griffin J, Mattos L, Lansky AJ, O’Neill WW, Grines CL (2001) Normal flow (TIMI-3) before mechanical reperfusion therapy is an independent determinant of survival in acute myocardial infarction. Clinical trial registrationĬ NCT03084991 (retrospectively registered). Systemic factors (older age and diabetes mellitus) and local factors (RCA location and macrophage accumulation) were independently associated with reduced coronary flow in STEMI patients with plaque erosion. In the multivariable analysis, age > 50 years, diabetes mellitus, RCA location, and macrophage accumulation were the independent predictors of reduced TIMI flow grade in STEMI patients with plaque erosion. TIMI 0–1 group had more lipid plaques (53.9% vs. 72.7%, P = 0.011), but more frequently located in the right coronary artery (RCA, 34.2% vs. Plaque erosion with TIMI flow 0–1 was less frequently located in the left anterior descending artery (LAD, 58.4% vs. Patients in TIMI 0–1 group were older (age > 50 years, 68.5% vs. A total of 329 ST-segment elevation myocardial infarction (STEMI) patients with optical coherence tomography (OCT) identified plaque erosion were divided into 2 groups by preprocedural TIMI flow grade. We aimed to identify the factors associated with reduced TIMI flow in plaque erosion. However, the pathological mechanism differs between plaque erosion and rupture. lipid burden) are related to preprocedural thrombolysis in myocardial infarction (TIMI) flow grade during primary percutaneous coronary intervention (PCI).
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